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Cell-laden cartilaginous tissues can be engineered in vitro and may provide a suitable graft material for cartilage repair. Such tissues are typically formed by multiplication of cells from an appropriate source (e.g., by monolayer culture starting at a low seeding density), differentiation of the cells to the chondrocytic phenotype, and then growth in vitro under controlled conditions. Compared to direct implantation of cells, such engineered tissues would be predicted to shorten the postoperative rehabilitation time because the processes of differentiation and matrix formation have already occurred or begun in vitro. Such tissues have been synthesized primarily with immature chondrocytes or chondroprogenitor cells, in combination with various types of scaffolds. Chondrogenic cells have often been mixed with or in ltrated into a number of scaffold materials to form cartilaginous tissue. Such materials are typically degradable and synthetic, such as polylactic acid [Dounchis et al., 2000] or polyglycolic
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A review of the organizational structure of a hotel shows that there are many departmental managers in a large organization. Which area is the best for you to enter to develop your career goals Four of the ports of entry are marketing and sales, front of ce, food and beverage, and controller. It is impossible to say which is the best port of entry; all are avenues for career development. The hotel industry demands a great deal from its professionals. All employees must have extensive knowledge of all areas of the facility, and they must understand the overall function of all departments. This understanding must be re ected in professional business plans. Employees must also have good communication skills and good interpersonal skills. The industry requires great exibility in scheduling work responsibilities and personal life. It demands that the professional understand the entrepreneurial role of the corporate owners while operating within budgeted resources. Students who enter the lodging industry will nd that each area in which they work contributes to a good background for the ultimate position of general manager. When
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These rst terrestrial systems provided what is termed local area coverage, even though this coverage can be quite large (this is the case for LORAN). However, some people imagined an even more ambitious project that would be the ultimate version of a terrestrial system with a global coverage: the Omega system. It was made up of eight stations using a very low frequency (VLF) band in order to have a complete coverage of the Earth. It was still a hyperbolic approach; each station transmitted sequentially, always in the same order for about 1 s (the duration of emission is speci c to each station). The emission consisted of pure continuous waves (no modulation scheme) at respectively 10.2, 11.33, and 13.6 kHz. The sequencing of transmission of these three frequencies was also speci c to each station. The total polling sequence lasted 10 s, and the synchronization was required to be better than 1 ms. To calculate an accurate location, it was also necessary to apply propagation corrections. These were based on long-period (typically 15 days) corrections depending on the date, the time of the day, and also on the estimated location. Once more, as we shall see later, the modern principle of satellite constellations was already present, only without the satellite aspects. The global accuracy was generally better than 8 km. The major reason for the poor accuracy of the abovementioned systems is included in propagation modeling (this point has constantly driven the evolution of modern systems). A new system was designed in order to reduce the propagation errors, and was called the differential Omega. The idea was simply to consider a receiver located in a well-known position, and which monitored the difference between the calculated location and the actual one. This difference was used as an error vector that could be subtracted from the calculated location of any receiver
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p-Nitrophenol Concentration (nmol/ml) 4.5 9.0 18 27 36 45 Volume (ml) of Diluted p-Nitrophenol Solution (50 nmol/ml) 0.1 0.2 0.4 0.6 0.8 1.0 Volume (ml) of 0.02 M NaOH 1.0 0.9 0.7 0.5 0.3 0.1
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If you previously backed up your e-mail folders onto a device like an external hard drive or a rewritable CD/DVD disc, then you must transfer those e-mail folders to your new computer. Be sure to copy them to My Documents or a similar location where they can be quickly and easily found.
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We have considered the problem of hypothesis testing in the classical setting, in which we treat the two probabilities of error separately. In the derivation of the Chernoff Stein lemma, we set n and achieved . n = 2 nD . But this approach lacks symmetry. Instead, we can follow a Bayesian approach, in which we assign prior probabilities to both
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Because battery technology is not improving very fast, the lifetime of a sensor node is increased primarily by reducing power consumption, rather than increasing supply. Low-power components help, but even very low-power microcontrollers and radios will drain a pair of AA batteries in a matter of days. Large-scale increases in node lifetime are obtained by turning components off during times when they are not needed. The duty cycle of a node is the fraction of the time that the node s high-power components are active, and may be on the order of 1%. This extends the lifetime of a node from several days to several months (Fig. 6.2). From the perspective of an operating system, power management comes in two avors: implicit and explicit. Implicit power management involves techniques that do not require cooperation from the user or from applications. Implicit power management is common in PCs. For example, laptop operating systems may dim the screen when running off battery power, and switch to full brightness when connected to an AC outlet. Many systems turn off components that have not been used for a long time (e.g., spinning down disks), and leave them off until needed. In both cases, neither the users nor the applications are involved in the power management decisions. Explicit power management is user- or application-directed. In an explicit power management scheme, the application uses a system call to give instructions or hints to the operating system. These calls may indicate which resources the application is going to use in the near future so that the operating system can determine which components need to be powered on. Explicit systems are inherently more ef cient than implicit ones, since the operating system has more information to work with. However, there is more work to be done by each application. In sensor nodes, one of the largest power consumers is the radio. The cost of transmitting one bit is on the order of a thousand times the cost of processing one bit. Despite power optimizations in other modules, the power consumed by radio transmission will continue to remain a concern because the laws of physics
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