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Current and previous medications, and their temporal relationship with obesity, should be documented. The main obesogenic drugs are shown in Table 15.2. If possible, obesogenic drugs should be withdrawn or their dosage reduced, or replaced by alternatives that do not cause weight gain (see Table 17.6). Patients taking atypical (second-generation) antipsychotic drugs deserve particular attention. Those with schizophrenia, the most common indication for these agents, have an increased risk of developing both diabetes and cardiovascular disease (Lean and Pajonk, 2003), and commonly have an unhealthy lifestyle (smoking, poor diet, inactivity and alcohol excess). Weight can increase rapidly with atypical antipsychotic drugs and may not reach a plateau for a year or more (American Diabetes Association, 2004). Patients therefore need to be counselled and monitored before and during treatment and, if possible, drugs that are less likely to cause weight gain and glucose intolerance should be
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A common feature at Linux events is a keysigning party where many people gather to verify and sign each other s GnuPG keys, thereby further strengthening the web of trust. The web of trust can work only if people are very careful about whose keys they sign. So, never sign a key for someone you have not met face to face. When meeting for the purpose of keysigning, always ask to see a drivers license or similar official photo ID and a hard copy of the key s fingerprint. If anything about the situation seems dubious, don t sign or your own reputation might suffer. If you do think the key is trustworthy, you can sign it with the edit-key option.
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Figure 5.13. DNA sequencing by chain termination (Sanger dideoxynucleotide sequencing), (a) DNA polymerase catalyses the synthesis of a DNA strand complementary to the DNA to be sequenced. When a ddNTP is incorporated, synthesis of the daughter strand ceases. P represents a radiolabel on the oligonucleotidc primer (which may be replaced by a uorescent label, see text), (b) A separate experiment is set up for each of four ddNTPs. This generates a set of truncated fragments in each test-tube. These are then electrophoresed through a polyacrylamide urea gel.
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+ 2Q,and (4.205) and (4.206) become
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Some of you might be thinking, Wait a second, what about the equalizing force of the Internet It brings color to all of us! Well, I concur wholeheartedly. Nearly everyone owns a color monitor, so we can all share color images freely. If this appeals to you, advance to 19 and learn how you can reduce color palettes and otherwise prepare your images for the bold new challenges of the Technicolor Web. Regardless of who you are print person or Web head color is a prime concern. Even gray values, after all, are colors. Many folks have problems accepting this premise I guess we re all so used to separating the worlds of grays and other colors in our minds that never the two shall meet. But gray values are only variations on what Noah Webster used to call The sensation resulting from stimulation of the retina of the eye by light waves of certain lengths. (Give the guy a few drinks and he d spout off 19 more definitions, not including the meanings of the transitive verb.) Just as black and white represent a subset of gray, gray is a subset of color. In fact, you ll find that using Photoshop involves a lot of navigating through these and other colorful subsets.
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can see a group of individuals sharing a physical medium. If Bob needs to send anything to Larry, he simply enters the MAC address (01:bb:04:af:00:1f) that is assigned to the NIC card on Larry s PC in the frame and sends it toward Larry s PC.
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Bending Energy The bending energy equation is also based on Hooke s law, where the k parameter controls the sti ness of the angle spring, while 0 de nes its equilibrium angle:
Frequency (MHz)
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