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FIGURE 6.1 Trends in power and size of electronic devices.
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. . . . . . 4.4.4 Post-Translational Modi cation Analysis of Proteins The post-translational modi cations summarized in Figure 4.26 and Table 4.3 are important to protein function because they may be implicated in processes such as protein activation/inactivation (e.g. protein phosphorylation in signal transduction cascades involving G-proteins), recognition (e.g. glycosylation of receptors) or proteolysis (e.g. protein turnover). Chemical procedures for analysis of individual modi cations such as glycosylation, acylation or phosphorylation exist. However, these techniques are laborious and only give information about a particular type of modi cation. The observation that all of the post-translational modi cations of proteins result in altered mass makes MS particularly suitable for their analysis. MS analysis of Oglyosylation is described in Example 4.4. DELETE FROM emp WHERE job= CLERK ;
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